Bioorganic Chemistry
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Course code
MLK6915.LT
old course code
MLK6915
Course title in Estonian
Bioorgaaniline keemia
Course title in English
Bioorganic Chemistry
ECTS credits
4.0
Assessment form
Examination
lecturer of 2022/2023 Autumn semester
lecturer not assigned
lecturer of 2022/2023 Spring semester
lecturer not assigned
Course aims
To be aware of structure-function relationships of biomolecules. The course is a connecting link between organic chemistry and biochemistry.
Brief description of the course
Bio-elements. Biologically essential organic compounds. Biopolymers and their complexes. The structure of biomolecules: configuration, cis/trans and optical isomeria, conformation and conformational changes. Heterofunctional organic compounds. Saccharides and proteins. The hierarchy of protein structures: primary, secondary, tertiary and quaternary structure. Enzymes. Heterocycles and nucleotides. Lipids (fatty acids, triglycerides, steroids and prostaglandins). Lipid aggregates: micells and lipoproteins. Bioregulators (hormones and vitamins). Physiologically active artificial compounds. Central biochemical reactions in human body. Experimental section: the purification and analysis of proteins, lipids and nucleic acids. The kinetics of enzyme catalysis.
Learning outcomes in the course
Upon completing the course the student:
- has knowledge about chemical foundations of biosphere by types of chemical compounds;
- has ability to differentiate and characterize structural aspects and levels of biologically important compounds;
- has ability to connect peculiarities of structure and functions of various types of bioactive compounds.
Teacher
dotsent Kalle Truus, PhD Tuuli Käämbre
Prerequisite course 1
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